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Vitamin C and Skin Health

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Vitamin C is an essential nutrient for skin as well as the rest of the body.  It’s absolutely necessary for normal skin and bodily functions, cannot be naturally synthesized in humans and must be provided externally. Skin itself has various critical roles in overall health including protection from dehydration and infection, and its appearance is an important reflection on general well-being. The epidermal layer of skin is responsible for most of its barrier function and includes many cells, particularly keratinocytes. In contrast, the lower dermal layer is composed mainly of fibroblasts that secrete the major component of the dermis, collagen...

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Increasing the Immune Defense of Skin

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The skin barrier, composed of lipids and essentially dead cells (corneocytes) in the upper layer of the epidermis (stratum corneum), plays a major role in protecting the body from numerous insults including microbial invasion. However, when compromised, the skin’s immune system is activated to defend the body from further damage and infection. Skin immunity involves the skin microbiome (collective set of microorganisms on the skin), antimicrobial peptides (short chains of amino acids) and a variety of signaling molecules that activate or suppress certain immune cells such as dendritic cells (including Langerhan’s cells), macrophages, neutrophils and mast cells.  When damage and/or...

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Decreasing Eczema to Help Reduce Pollen Allergies and Asthma

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Eczema or atopic dermatitis is a common inflammatory skin condition that can result in serious itching (pruritus), lack of sleep, embarrassment and psychological stress. The lifetime prevalence of eczema has increased worldwide for the past 30 years, and recently the prevalence for adults was estimated to be approximately 10% of the population.  Viniferamine® skin and wound care products contain potent anti-inflammatory small molecule ingredients that can help decrease pruritus including the beneficial polyphenols oleuropein, resveratrol, and epigallocatechin-3-gallate (EGCG) from olives, grapes, and green tea, respectively, as well as the important small molecules, melatonin, and L-glutathione. In addition, dipotassium glycyrrhizate from licorice,...

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